2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Epigenetics Stem Cell/Wnt Apoptosis
  3. JAK STAT Apoptosis
  4. DPP

DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety.

For research use only. We do not sell to patients.

DPP Chemical Structure

DPP Chemical Structure

CAS No. : 2668267-47-6

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DPP Related Antibodies

Top Publications Citing Use of Products

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JAK1 JAK2 JAK3 Tyk2 JAK

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STAT3 STAT5 STAT6 STAT1

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Description

DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].

Molecular Weight

926.70

Formula

C36H40Cl2N2O10Pt
CAS No.
SMILES

COC1=CC(OC)=CC(/C=C/C(C=C2)=CC=C2OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[O-]C(COC(C=C3)=CC=C3/C=C/C4=CC(OC)=CC(OC)=C4)=O)=O)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DPP Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DPP2668267-47-6JAKSTATApoptosisJanus kinaseInhibitorinhibitorinhibit

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