2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. DR4485 hydrochloride

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14).

For research use only. We do not sell to patients.

DR4485 hydrochloride Chemical Structure

DR4485 hydrochloride Chemical Structure

CAS No. : 402942-53-4

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Based on 1 publication(s) in Google Scholar

DR4485 hydrochloride Related Antibodies

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Description

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14)[1].

IC50 & Target[1]

5-HT7 Receptor

8.14 (pKi)

In Vitro

DR4485 (MZ54 WT cells; 6 µM or 8 µM) hydrochloride induces autophagy as well as cell death that is diminished by KO of ATG5 and ATG7[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DR4485 hydrochloride Related Antibodies
Molecular Weight

491.88

Formula

C26H29Cl3N2O
CAS No.
SMILES

O=C1NC2=C3C1(CCCCN4CC=C(C5=CC=C(Cl)C=C5)CC4)CCCC3=C(Cl)C=C2.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DR4485 hydrochloride Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DR4485402942-53-4DR 4485DR-44855-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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DR4485 hydrochloride
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HY-103126
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