2. Apoptosis
  3. TNF Receptor
  4. DRI-C21041

DRI-C21041 is a CD40/CD40L interaction inhibitor, with an IC50 of 0.31 μM. DRI-C21041 inhibits the immune response induced by alloantigen.

For research use only. We do not sell to patients.

DRI-C21041 Chemical Structure

DRI-C21041 Chemical Structure

CAS No. : 2101765-78-8

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DRI-C21041 Related Antibodies

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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Description

DRI-C21041 is a CD40/CD40L interaction inhibitor, with an IC50 of 0.31 μM. DRI-C21041 inhibits the immune response induced by alloantigen[1].

IC50 & Target[1]

CD40L

0.31 μM (IC50)

In Vitro

DRI-C21041 inhibits CD40L-induced B-cell activation, proliferation, and the activation of NF-κB[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DRI-C21041 Related Antibodies
Molecular Weight

567.57

Formula

C30H21N3O7S
CAS No.
SMILES

O=S(C1=C2C(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C([N+]([O-])=O)C=C5)=O)C=C4)C=C3)=O)=CC=CC2=CC=C1)(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DRI-C21041 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DRI-C210412101765-78-8TNF ReceptorTumor Necrosis Factor ReceptorTNFRimmune responseInhibitorinhibitorinhibit

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