Drimentine C

Cat. No.: HY-125092: FAQs
Data Sheet Handling Instructions Technical Support

Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 μg/mL, respectively.

For research use only. We do not sell to patients.

Drimentine C Chemical Structure

CAS No. : 204398-92-5

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Biological Activity
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References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	> 10 μM Compound: 4	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 23547884]
A549	IC₅₀	> 10 μM Compound: 4	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 23547884]
Bel-7402	IC₅₀	> 10 μM Compound: 4	Cytotoxicity against human Bel7402 cells by MTT assay Cytotoxicity against human Bel7402 cells by MTT assay	[PMID: 23547884]
BGC-823	IC₅₀	> 10 μM Compound: 4	Cytotoxicity against human BGC823 cells by MTT assay Cytotoxicity against human BGC823 cells by MTT assay	[PMID: 23547884]
HCT-8	IC₅₀	> 10 μM Compound: 4	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 23547884]

Molecular Weight

487.68

Formula

C₃₁H₄₁N₃O₂

CAS No.

204398-92-5

SMILES

O=C(N1CCC[C@]1(C2=O)[H])[C@]3(N2[C@]4([C@@](C[C@]5(C(CC[C@@]6([C@@]5(CCCC6(C)C)C)[H])=C)[H])(C3)C7=C(N4)C=CC=C7)[H])[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lacey, et al. Terpenylated diketopiperazines, (drimentines). WO1998009968A1,(1998).

Drimentine C Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Drimentine C204398-92-5AntibioticInhibitorinhibitorinhibit

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