DSPE-PEG-DBCO ammonium 

DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research^[1].

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.?

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(C₂H₄O)_nC₆₃H₁₀₀N₃O₁₂P.H₃N

2052955-83-4

Solid

White to off-white

O=C(CCNC(CCOCCOC(NCCOP(OC[C@@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O)N1C2=CC=CC=C2C#CC3=CC=CC=C3C1.N.[n]

Room temperature in continental US; may vary elsewhere.

• [1]. Borden MA, et al., Aseptic process for azido-functionalized ligand conjugation to size-isolated microbubbles via strain-promoted azide-alkyne cycloaddition. WO2019195463.