1. Metabolic Enzyme/Protease
  2. Liposome
  3. DSPE-PEG-OH, MW 2000

DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery.

For research use only. We do not sell to patients.

DSPE-PEG-OH, MW 2000 Chemical Structure

DSPE-PEG-OH, MW 2000 Chemical Structure

Size Price Stock Quantity
25 mg USD 110 In-stock
50 mg USD 180 In-stock
100 mg USD 300 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE DSPE-PEG-OH, MW 2000

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery[2].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2000(Average)

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCC(OCC(OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCOCCOCCO)=O)(O)=O)=O.[n].[MW 2000]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 100 mg/mL (Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
DSPE-PEG-OH, MW 2000
Cat. No.:
HY-140741
Quantity:
MCE Japan Authorized Agent: