2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. DTP348

DTP348 is an inhibitor for carbonic anhydrase IX with a Ki of 8.3 nM in vitro and an IC50 of 19.26 μM in Xenopus oocytes. DTP348 exhibits slight toxicity in zebrafish embryos with LD50 of 3.5 mM. DTP348 can be used in the anti-cancer research.

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DTP348 Chemical Structure

DTP348 Chemical Structure

CAS No. : 1383370-92-0

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DTP348 Related Antibodies

Top Publications Citing Use of Products

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

DTP348 is an inhibitor for carbonic anhydrase IX with a Ki of 8.3 nM in vitro and an IC50 of 19.26 μM in Xenopus oocytes. DTP348 exhibits slight toxicity in zebrafish embryos with LD50 of 3.5 mM. DTP348 can be used in the anti-cancer research[1].

IC50 & Target

CA Ⅸ

8.3 nM (Ki)

Molecular Weight

249.25

Formula

C6H11N5O4S
CAS No.
SMILES

O=S(NCCN1C([N+]([O-])=O)=CN=C1C)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DTP348 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DTP3481383370-92-0DTP 348DTP-348Carbonic AnhydraseCarbonate dehydrataseXenopuszebrafishInhibitorinhibitorinhibit

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