2. Anti-infection
  3. HBV
  4. DVR-01

DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases.

For research use only. We do not sell to patients.

DVR-01 Chemical Structure

DVR-01 Chemical Structure

CAS No. : 330461-34-2

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Based on 1 publication(s) in Google Scholar

DVR-01 Related Antibodies

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Description

DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases[1].

In Vitro

DVR-01 (0-10 μM; 4 d) inhibits HBV in human hepatoma cells with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively[1].
DVR-01 (0.156-10 μM; 2 d) selectively disrupts the pgRNA encapsidation by HBV[1].
DVR-01 (3 d) shows antiviral activity against hepadnaviruses in human hepatoma cells with EC50s of 2.899, ＞10 and ＞25 μM for HBV, WHV and DHBV, respectively[1].
DVR-01 (0.0097-10 μM; 2 d) shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.899, 3.273, 3.180, 2.752, 2.567 and 2.403 μM for wt, rtL180 M/rtM204V, rtA181V, rtN236T, rtM204I and rtL180 M/rtM204V/rtT184G/rtS202I, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DVR-01 Related Antibodies
Molecular Weight

406.93

Formula

C20H23ClN2O3S
CAS No.
SMILES

O=C(NCC1=CC=CC=C1)C2=CC=C(C(S(N3CCCCCC3)(=O)=O)=C2)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DVR-01 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DVR-01330461-34-2DVR01DVR 01HBVHepatitis B virusAML12HBV10HepDES19hepatoma cellpgRNA encapsidationhepadnaviruseHBV mutantInhibitorinhibitorinhibit

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