2. Anti-infection
  3. Antibiotic Bacterial
  4. (E)-Aztreonam

(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic. (E)-Aztreonam has the potential for the research of infections caused by gram-negative pathogens.

For research use only. We do not sell to patients.

(E)-Aztreonam Chemical Structure

(E)-Aztreonam Chemical Structure

CAS No. : 99341-02-3

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Other Forms of (E)-Aztreonam:

(E)-Aztreonam Related Antibodies

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Description

(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic. (E)-Aztreonam has the potential for the research of infections caused by gram-negative pathogens[1][2][3].

In Vivo

(E)-Aztreonam (28 mg/kg; i.p.; daily for 14 days) induces an increased level of cellular activation in peritoneal cells, increasing the capacity of IL-1 production by peritoneal macrophages in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks, male BALB/c mice[3]
Dosage: 7, 14, 28, 57 mg/kg
Administration: I.p.; daily for 7 days, 28 mg/kg daily for 14 days
Result: Increased every immune parameter treatment with 28 mg/kg per day of aztreonam over 14 days, treatment with 57 mg/kg per day of aztreonam for 7 days only enhanced the natural killer (NK) activity of splenocytes.
Molecular Weight

435.43

Formula

C13H17N5O8S2
CAS No.
SMILES

CC(C)(O/N=C(C1=CSC(N)=N1)/C(N[C@H]2[C@H](C)N(S(=O)(O)=O)C2=O)=O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(E)-Aztreonam Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-Aztreonam99341-02-3SQ-28429SQ28429SQ 28429AntibioticBacterialmonobactamantibioticIL-1 productionInhibitorinhibitorinhibit

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