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  4. (E)-L-652343

(E)-L-652343 is a compound with potent cyclooxygenase and 5-lipoxygenase inhibitory activity. (E)-L-652343 can effectively inhibit the synthesis of products of these two pathways in vivo. (E)-L-652343 showed high sensitivity and specificity in the detection of geometric isomers in canine and human plasma. (E)-L-652343 showed selective metabolism in vivo, and the elimination rate of the E isomer was faster than that of the Z isomer.

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(E)-L-652343 Chemical Structure

(E)-L-652343 Chemical Structure

CAS No. : 102565-09-3

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Description

(E)-L-652343 is a compound with potent cyclooxygenase and 5-lipoxygenase inhibitory activity. (E)-L-652343 can effectively inhibit the synthesis of products of these two pathways in vivo. (E)-L-652343 showed high sensitivity and specificity in the detection of geometric isomers in canine and human plasma. (E)-L-652343 showed selective metabolism in vivo, and the elimination rate of the E isomer was faster than that of the Z isomer[1].

Molecular Weight

445.48

Formula

C22H14F3NO2S2
CAS No.
SMILES

O=C(C1=C(O)C2=CC(C(F)(F)F)=CC=C2S1)N/C=C(C3=CC=CC=C3)/C4=CC=CS4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(E)-L-652343 Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

(E)-L-652343102565-09-3OthersInhibitorinhibitorinhibit

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