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  3. (E/Z)-BIX02189

(E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

(E/Z)-BIX02189 Chemical Structure

(E/Z)-BIX02189 Chemical Structure

CAS No. : 1094614-85-3

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

(E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

BIX 02189 is a selective MEK5 inhibitor with IC50 of 1.5 nM, also inhibits the catalytic activity of ERK5 with IC50 of 810 nM, without inhibiting its closely related kinases MEK1, MEK2, ERK2, and JNK2.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

440.54

Formula

C27H28N4O2

CAS No.
SMILES

O=C(N(C)C)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(E/Z)-BIX02189
Cat. No.:
HY-12056A
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