1. Membrane Transporter/Ion Channel
  2. Calmodulin
  3. E6 Berbamine

E6 Berbamine  (Synonyms: Berbamine p-nitrobenzoate)

Cat. No.: HY-120997
Handling Instructions

E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activity of calmodulin (CaM)-dependent myosin light chain kinase (MLCK), with a Ki of 0.95 μM. E6 Berbamine also shows anti-leukemia activities, with an IC50 of 2.13 μM in K562 cells.

For research use only. We do not sell to patients.

E6 Berbamine Chemical Structure

E6 Berbamine Chemical Structure

CAS No. : 114784-59-7

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Description

E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activity of calmodulin (CaM)-dependent myosin light chain kinase (MLCK), with a Ki of 0.95 μM[1]. E6 Berbamine also shows anti-leukemia activities, with an IC50 of 2.13 μM in K562 cells[2].

Molecular Weight

757.83

Formula

C44H43N3O9

CAS No.
SMILES

COC1=C(OC2=CC3=C(C=C2OC)CCN4C)C5=C(C=C1OC)CCN(C)[C@@]5(CC6=CC=C(C(OC7=CC=C(C=C7)C[C@@]34[H])=C6)OC(C8=CC=C(C=C8)[N+]([O-])=O)=O)[H]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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E6 Berbamine
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