EC1167 hydrochloride

Cat. No.: HY-128938A Purity: 98.04%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC).

For research use only. We do not sell to patients.

EC1167 hydrochloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 480	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1450	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 2250	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of EC1167 hydrochloride:

EC1167 Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

880.27

Formula

C₃₃H₄₆ClN₇O₁₇S

Appearance

Solid

Color

White to off-white

SMILES

SC[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC(CC1=CC=C(CNC(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)C=C1)=O)=O)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (142.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1360 mL	5.6801 mL	11.3602 mL
5 mM	0.2272 mL	1.1360 mL	2.2720 mL
10 mM	0.1136 mL	0.5680 mL	1.1360 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.04%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (245 KB) HNMR (382 KB) RP-HPLC (227 KB) MS (181 KB)

Handling Instructions (2659 KB)

References

[1]. Leamon CP, et al. Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate. Bioconjug Chem. 2019 Jun 19;30(6):1805-1813. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1360 mL	5.6801 mL	11.3602 mL	28.4004 mL
	5 mM	0.2272 mL	1.1360 mL	2.2720 mL	5.6801 mL
	10 mM	0.1136 mL	0.5680 mL	1.1360 mL	2.8400 mL
	15 mM	0.0757 mL	0.3787 mL	0.7573 mL	1.8934 mL
	20 mM	0.0568 mL	0.2840 mL	0.5680 mL	1.4200 mL
	25 mM	0.0454 mL	0.2272 mL	0.4544 mL	1.1360 mL
	30 mM	0.0379 mL	0.1893 mL	0.3787 mL	0.9467 mL
	40 mM	0.0284 mL	0.1420 mL	0.2840 mL	0.7100 mL
	50 mM	0.0227 mL	0.1136 mL	0.2272 mL	0.5680 mL
	60 mM	0.0189 mL	0.0947 mL	0.1893 mL	0.4733 mL
	80 mM	0.0142 mL	0.0710 mL	0.1420 mL	0.3550 mL
	100 mM	0.0114 mL	0.0568 mL	0.1136 mL	0.2840 mL