1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Liposome Folate Receptor (FR)
  3. EC1454

EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy.

For research use only. We do not sell to patients.

EC1454 Chemical Structure

EC1454 Chemical Structure

CAS No. : 1602487-15-9

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Description

EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy[1].

Molecular Weight

1679.63

Formula

C65H98N16O34S

CAS No.
SMILES

O=C1C2=NC(CNC3=CC=C(C(N[C@@H](C(O)=O)CCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EC1454
Cat. No.:
HY-128937
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