EDTA-OH

Cat. No.: HY-W013851 Purity: 97.11%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils. EDTA-OH is able to cross brain-blood barrier.

For research use only. We do not sell to patients.

EDTA-OH Chemical Structure

CAS No. : 150-39-0

Size	Price	Stock
5 g	USD 25	Ask For Quote & Lead Time
25 g	USD 30	Ask For Quote & Lead Time

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Purity & Documentation
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Description

EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper^[1]. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils^[2]. EDTA-OH is able to cross brain-blood barrier^[3].

In Vivo

EDTA-OH (50 mg/kg, i.p. for 5 days) decreases the aluminium concentration in blood and brain and oxidative stress in brain. EDTA-OH is blood-brain barrier permeable, which could be an antidote for aluminium overload^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Aluminium overload in wistar rats^[3]
Dosage:	50 mg/kg
Administration:	i.p. for 5 days
Result:	Inhibited GST activity, reduced the concentration of aluminium in blood and brain.

Molecular Weight

278.26

Formula

C₁₀H₁₈N₂O₇

CAS No.

150-39-0

Appearance

Solid

SMILES

O=C(O)CN(CCO)CCN(CC(O)=O)CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 5 mg/mL (17.97 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5938 mL	17.9688 mL	35.9376 mL
5 mM	0.7188 mL	3.5938 mL	7.1875 mL
10 mM	0.3594 mL	1.7969 mL	3.5938 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 97.11%

Select Batch:

Data Sheet (272 KB) SDS (614 KB)

COA (247 KB) HNMR (124 KB) LCMS (237 KB)

Handling Instructions (2659 KB)

References

[1]. Li X, Zhang Z, et al., Complexation of Light Trivalent Lanthanides with N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic Acid in Aqueous Solutions: Thermodynamic Analysis and Coordination Modes. Inorg Chem. 2019 Nov 18;58(22):15618-15628. [Content Brief]

[2]. Chen H, et al., EDTA and HEDTA effects on Cd, Cr, and Ni uptake by Helianthus annuus. Chemosphere. 2001 Oct;45(1):21-8. [Content Brief]

[3]. Flora SJ, et al., Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Mar;134(3):319-28. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.5938 mL	17.9688 mL	35.9376 mL	89.8440 mL
	5 mM	0.7188 mL	3.5938 mL	7.1875 mL	17.9688 mL
	10 mM	0.3594 mL	1.7969 mL	3.5938 mL	8.9844 mL
	15 mM	0.2396 mL	1.1979 mL	2.3958 mL	5.9896 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

EDTA-OH Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EDTA-OH150-39-0Biochemical Assay Reagentsbrain-blood barrierphytoremediationwistar ratInhibitorinhibitorinhibit

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