2. Biochemical Assay Reagents
  3. Chelators

Chelators

Chelators refer to a class of compounds capable of forming complexes with metal ions. They contain two or more ligands that react with metal ions to form stable chelates. Typically, chelators possess multiple functional groups, such as quaternary ammonium and amino groups, which can encapsulate metal ions within the molecule. This encapsulation reduces the catalytic performance of metal ions, thereby mitigating their influence on reactions.
Chelators are widely used in the fields of pharmaceutical preparations, cosmetics and food to regulate pH values and enhance stability.

Chelators (151):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-100545
    BAPTA-AM 126150-97-8 99.68%
    BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively.
    BAPTA-AM
  • HY-D0861
    EGTA 67-42-5 ≥98.0%
    EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages.
    EGTA
  • HY-100168
    BAPTA 85233-19-8 98.10%
    BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
    BAPTA
  • HY-Y0682
    Ethylenediaminetetraacetic acid 60-00-4 ≥98.0%
    Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research.
    Ethylenediaminetetraacetic acid
  • HY-W004544
    o-Phenanthroline 66-71-7 99.96%
    o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor.
    o-Phenanthroline
  • HY-W018746
    EDTA disodium 139-33-3 ≥98.0%
    EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
    EDTA disodium
  • HY-Y0262B
    Sodium oxalate,ACS,99.5% 62-76-0 ≥99.0%
    Sodium oxalate,ACS,99.5% (Ethanedioic acid (sodium),ACS, 99.5%) is a biochemical assay reagent.
    Sodium oxalate,ACS,99.5%
  • HY-W009722
    Sodium diethylcarbamodithioate trihydrate 20624-25-3 ≥98.0%
    Sodium diethylcarbamodithioate trihydrate is an organic compound commonly used as an accelerator in rubber processing. It can be used to accelerate the vulcanization reaction of natural rubber and synthetic rubber, and is widely used in rubber manufacturing. In addition, this compound can also be used as a reagent and catalyst in some organic synthesis reactions.
    Sodium diethylcarbamodithioate trihydrate
  • HY-W004563
    Neocuproine 484-11-7 99.82%
    Neocuproine is an organic compound commonly used as a complexing reagent and copper ion detector. It can form stable complexes with copper ions, and can play a catalytic role in certain chemical reactions and analytical methods. In addition, this compound is also widely used in some biomedical fields, such as in the study of copper metabolism disorders and neurodegenerative diseases
    Neocuproine
  • HY-D0973
    EGTA-AM 99590-86-0
    EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics.
    EGTA-AM
  • HY-D0180
    18-Crown-6-ether 17455-13-9 99.57%
    18-Crown-6-ether (18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane) is an organic compound that can be used to prepare stable microcapsule responsive layers for further assembly into bilayer microcapsules. For example, 18-Crown-6-ether is used to prepare the response layer and is coated with a G-quadruplex cross-linked hydrogel layer stabilized by K+; when Mg2+ ions are present, 18-Crown-6-ether and K+ ions can respectively Dissociates and locks with the G-quadruplex cross-linked layer, thereby achieving switchable controlled release of the load.
    18-Crown-6-ether
  • HY-100168B
    BAPTA tetrapotassium 73630-08-7 99.45%
    BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
    BAPTA tetrapotassium
  • HY-B0812
    5-Sulfosalicylic acid dihydrate 5965-83-3 99.88%
    5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid dihydrate is effective against the breast cancer cell line, MCF-7, with less toxicity. 5-Sulfosalicylic acid dihydrate has antioxidant activities.
    5-Sulfosalicylic acid dihydrate
  • HY-A0074
    DTPA-tetra (t-Bu ester) 174267-71-1 ≥99.0%
    DTPA-tetra (t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DPTA derivative used for tumor pre-targeting. DTPA-tetra (t-Bu ester) can be used for conjugation of peptides and radionuclides.
    DTPA-tetra (t-Bu ester)
  • HY-W015236
    H-Gly-Gly-Gly-OH 556-33-2 99.26%
    H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
    H-Gly-Gly-Gly-OH
  • HY-W127785
    N-ethyl-N-oxido-dodecan-1-amine 1643-20-5
    N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
    N-ethyl-N-oxido-dodecan-1-amine
  • HY-W250574
    NOTA-bis(tBu)ester 1161415-28-6
    NOTA-bis(tBu)ester (NOTA-bis(t-Butyl ester)), a NOTA derivative, is a bifunctional chelator that can be used for drug coupling.
    NOTA-bis(tBu)ester
  • HY-D0836
    EDTA dipotassium dihydrate 25102-12-9 ≥99.0%
    EDTA (Ethylenediaminetetraacetic acid) dipotassium dihydrate is anticoagulants, chelating heavy metal and relieve toxicity. EDTA dipotassium dihydrate can damage chromosomes, interfere with the DNA repair process, increase the incidence of meiosis exchange.
    EDTA dipotassium dihydrate
  • HY-W283556
    DO2A-tert-butyl ester 162148-48-3 ≥98.0%
    DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers.
    DO2A-tert-butyl ester
  • HY-111413A
    c(phg-isoDGR-(NMe)k) TFA 99.88%
    c(phg-isoDGR-(NMe)k) TFA is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM.
    c(phg-isoDGR-(NMe)k) TFA