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EGA is a selective inhibitor of endosomol trafficking pathways exploited by multiple toxins and virus[1].

For research use only. We do not sell to patients.

EGA Chemical Structure

EGA Chemical Structure

CAS No. : 415687-81-9

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5 mg USD 220 In-stock
10 mg USD 360 In-stock
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Based on 1 publication(s) in Google Scholar

EGA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE EGA

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Description

EGA is a selective inhibitor of endosomol trafficking pathways exploited by multiple toxins and virus[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
1.4 μM
Compound: 1, EGA
Inhibition of Bacillus anthracis lethal toxin-induced mouse RAW264.7 cell death preincubated for 1 hr followed by lethal toxin challenge measured after 4 hrs
Inhibition of Bacillus anthracis lethal toxin-induced mouse RAW264.7 cell death preincubated for 1 hr followed by lethal toxin challenge measured after 4 hrs
[PMID: 24900841]
Molecular Weight

346.22

Formula

C16H16BrN3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

BrC1=CC=C(/C=N/NC(NC2=C(C)C=CC=C2C)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (28.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8883 mL 14.4417 mL 28.8834 mL
5 mM 0.5777 mL 2.8883 mL 5.7767 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

SDS (537 KB)

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8883 mL 14.4417 mL 28.8834 mL 72.2084 mL
5 mM 0.5777 mL 2.8883 mL 5.7767 mL 14.4417 mL
10 mM 0.2888 mL 1.4442 mL 2.8883 mL 7.2208 mL
15 mM 0.1926 mL 0.9628 mL 1.9256 mL 4.8139 mL
20 mM 0.1444 mL 0.7221 mL 1.4442 mL 3.6104 mL
25 mM 0.1155 mL 0.5777 mL 1.1553 mL 2.8883 mL
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EGA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGA415687-81-9OthersInhibitorinhibitorinhibit

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