1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR
  3. EGFR/c-Met-IN-2

EGFR/ C-Met-in-2 (Compound H-22) is a dual inhibitor of EGFR/c-Met. EGFR/c-Met-IN-2 inhibits cell proliferation by arresting G2/M phase. EGFR/c-Met-IN-2 has antitumor activity.

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EGFR/c-Met-IN-2 Chemical Structure

EGFR/c-Met-IN-2 Chemical Structure

CAS No. : 2761180-01-0

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Description

EGFR/ C-Met-in-2 (Compound H-22) is a dual inhibitor of EGFR/c-Met. EGFR/c-Met-IN-2 inhibits cell proliferation by arresting G2/M phase. EGFR/c-Met-IN-2 has antitumor activity[1].

Molecular Weight

519.50

Formula

C27H23F2N5O4

CAS No.
SMILES

O=C(C=C)NC(C(OC)=C1)=CC2=C1N=CN=C2OC3=CC=C(NC(NCCC4=CC=C(F)C=C4)=O)C=C3F

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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EGFR/c-Met-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
EGFR/c-Met-IN-2
Cat. No.:
HY-161141
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