2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR/HER2-IN-13

EGFR/HER2-IN-13 (Compd 38) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-13 can be used for cancer research.

For research use only. We do not sell to patients.

EGFR/HER2-IN-13 Chemical Structure

EGFR/HER2-IN-13 Chemical Structure

CAS No. : 3034701-46-4

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EGFR/HER2-IN-13 Related Antibodies

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Description

EGFR/HER2-IN-13 (Compd 38) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-13 can be used for cancer research[1].

In Vitro

EGFR/HER2-IN-13 shows IC50s bellow 100 nM against insASV, insSVD, insGSP mutants EGFRs transformed Ba/F3 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EGFR/HER2-IN-13 Related Antibodies
Molecular Weight

520.63

Formula

C27H36N8O3
CAS No.
SMILES

CN1C2=NC(NC3=C(OC)C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C3)=NC=C2CN(C45CC(C5)C4)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR/HER2-IN-13 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR/HER2-IN-133034701-46-4EGFREpidermal growth factor receptorErbB-1HER1drug resistantEGFR/HER2Inhibitorinhibitorinhibit

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EGFR/HER2-IN-13
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