1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  2. EGFR
  3. EGFR-IN-103

EGFR-IN-103 (compound 1) is a potent EGFR inhibitor with an IC50 of 6 nM for pEGFR.

For research use only. We do not sell to patients.

EGFR-IN-103 Chemical Structure

EGFR-IN-103 Chemical Structure

CAS No. : 2568506-66-9

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Description

EGFR-IN-103 (compound 1) is a potent EGFR inhibitor with an IC50 of 6 nM for pEGFR[1].

Molecular Weight

612.51

Formula

C28H24Cl2FN7O2S

CAS No.
SMILES

O=C(NC1=NC=CS1)C(N2N=C3C(C(Cl)=CC(C4=CC=C(N5CCOCC5)C=C4)=C3Cl)=C2)C6=C7N(C[C@@H](C7)F)C=N6

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
EGFR-IN-103
Cat. No.:
HY-163354
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