2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-IN-115

EGFR-IN-115 (H-13) is an EGFR inhibitor, with IC50 of 395.2 nM. EGFR-IN-115 can be used in anti-cancer research.

For research use only. We do not sell to patients.

EGFR-IN-115 Chemical Structure

EGFR-IN-115 Chemical Structure

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EGFR-IN-115 Related Antibodies

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Description

EGFR-IN-115 (H-13) is an EGFR inhibitor, with IC50 of 395.2 nM. EGFR-IN-115 can be used in anti-cancer research[1].

IC50 & Target

EGFR

395.2 nM (IC50)

Molecular Weight

656.77

Formula

C35H44N8O5
SMILES

O=C(C1=CN=C(NC2=CC(NC(NC3CCN(C)CC3)=O)=C(N4CCOCC4)C=C2OC)N=C1C5=CN(C)C6=C5C=CC=C6)OC(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR-IN-115 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-115EGFREpidermal growth factor receptorErbB-1HER1Antitumor activity evaluationDrug synthesisEGFR inhibitorMobocertinib derivativeNon-small cell lung cancerT790M mutationInhibitorinhibitorinhibit

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EGFR-IN-115
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HY-162602
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