2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR T790M/L858R-IN-6

EGFR T790M/L858R-IN-6 (compound 53), a pyrimidine compound, is a potent EGFR T790M/L858R inhibitor. EGFR T790M/L858R-IN-6 shows 90.88% enzyme activity inhibition with 0.05 μM.

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EGFR T790M/L858R-IN-6 Chemical Structure

EGFR T790M/L858R-IN-6 Chemical Structure

CAS No. : 3032760-71-4

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EGFR T790M/L858R-IN-6 Related Antibodies

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Description

EGFR T790M/L858R-IN-6 (compound 53), a pyrimidine compound, is a potent EGFR T790M/L858R inhibitor. EGFR T790M/L858R-IN-6 shows 90.88% enzyme activity inhibition with 0.05 μM[1].

IC50 & Target[1]

EGFR (L858R/T790M)

 

Molecular Weight

481.55

Formula

C27H27N7O2
CAS No.
SMILES

OCCNC1=CC(OC)=C(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)C=C1NC5=NC=CC=C5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR T790M/L858R-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR T790M/L858R-IN-63032760-71-4EGFREpidermal growth factor receptorErbB-1HER1PyrimidineT790ML858RInhibitorinhibitorinhibit

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