2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-TK-IN-3

EGFR-TK-IN-3 (3) is an EGFR TK inhibitor, with an IC50 of 2.33 μM against Erlotinib (HY-50896)-resistant A549 cells.

For research use only. We do not sell to patients.

EGFR-TK-IN-3 Chemical Structure

EGFR-TK-IN-3 Chemical Structure

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EGFR-TK-IN-3 Related Antibodies

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Description

EGFR-TK-IN-3 (3) is an EGFR TK inhibitor, with an IC50 of 2.33 μM against Erlotinib (HY-50896)-resistant A549 cells[1].

In Vitro

The compound’s mechanism of anticancer action involves acombination of EGFR TK inhibitory activity and the capability to generatereactive oxygen species in lung cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EGFR-TK-IN-3 Related Antibodies
Molecular Weight

722.65

Formula

C38H46FeN6O5
SMILES

O=C(c1cccc1)CN2C=C(N=N2)C3=CC(NC4=NC=NC5=CC(OCCOC)=C(C=C54)OCCOC)=CC=C3.CC.CC.c6cccc6.[Fe]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR-TK-IN-3 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-TK-IN-3EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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EGFR-TK-IN-3
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HY-163860
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