2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. EGIS-7625

EGIS-7625 is a selective and competitive 5-HT2B inhibitor with pKi values of 9.0, 6.2, 7.7 for 5-HT2B, 5-HT2A, 5-HT2C, respective. EGIS-7625 partially attenuates m-chlorophenylpiperazine-induced hypomotility and hypophagia.

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EGIS-7625 Chemical Structure

EGIS-7625 Chemical Structure

CAS No. : 755040-97-2

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EGIS-7625 Related Antibodies

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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Description

EGIS-7625 is a selective and competitive 5-HT2B inhibitor with pKi values of 9.0, 6.2, 7.7 for 5-HT2B, 5-HT2A, 5-HT2C, respective. EGIS-7625 partially attenuates m-chlorophenylpiperazine-induced hypomotility and hypophagia[1].

IC50 & Target[1]

5-HT2B Receptor

9.0 (pKi)

5-HT2A Receptor

6.2 (pKi)

5-HT2C Receptor

7.7 (pKi)

Molecular Weight

399.31

Formula

C18H24Cl2N4O2
CAS No.
SMILES

NC1=CC(N2CCN(CC3=CC=CC=C3)CC2)=C([N+]([O-])=O)C=C1C.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGIS-7625 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGIS-7625755040-97-2EGIS7625EGIS 76255-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorcompetitivehypomotilityhypophagiaInhibitorinhibitorinhibit

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