Elinogrel potassium  (Synonyms: PRT060128 potassium)

Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y₁₂ antagonist. Elinogrel potassium inhibits thrombosis^[1][2].

Elinogrel (60 mg/kg; p.o.; daily for 3 days) inhibits thrombosis^[2].
Elinogrel (1 mg/kg; i.v.) blocks residual thrombotic activity observed in clopidogrel (HY-15283)-treated mice (50 mg/kg p.o., 3 days) in a FeCl3 (HY-Y0266)-induced vascular injury model^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

563.04

C₂₀H₁₅ClFKN₅O₅S₂

936501-01-8

O=S(C1=CC=C(Cl)S1)(NC(NC2=CC=C(N3C(NC4=C(C=C(F)C(NC)=C4)C3=O)=O)C=C2)=O)=O.[K]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ueno M, et al. Elinogrel: pharmacological principles, preclinical and early phase clinical testing. Future Cardiol. 2010 Jul;6(4):445-53.  [Content Brief]

  [2]. Haberstock-Debic H, et al. A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61.  [Content Brief]