1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Embusartan

Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension.

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Embusartan Chemical Structure

Embusartan Chemical Structure

CAS No. : 156001-18-2

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Description

Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension[1].

Molecular Weight

461.49

Formula

C25H24FN5O3

CAS No.
SMILES

O=C(C(C=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2F)=CC1=O)OC

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Embusartan
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HY-121313
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