2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. Antibody-Drug Conjugates (ADCs) EGFR TAM Receptor
  4. Enapotamab vedotin

Enapotamab vedotin is an AXL-targeted antibody-drug conjugate with inhibitory potential against non-small cell lung cancer (NSCLC). Enapotamab vedotin also targets the PDX models resistant to EGFR mutations and EGFR inhibitor (osimertinib).

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Enapotamab vedotin Chemical Structure

Enapotamab vedotin Chemical Structure

CAS No. : 1912424-97-5

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Enapotamab vedotin Related Antibodies

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Axl Mer Tyro3

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Description

Enapotamab vedotin is an AXL-targeted antibody-drug conjugate with inhibitory potential against non-small cell lung cancer (NSCLC). Enapotamab vedotin also targets the PDX models resistant to EGFR mutations and EGFR inhibitor (osimertinib)[1].

IC50 & Target

AXL[1]
CAS No.
SMILES

[Enapotamab vedotin]
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Enapotamab vedotin Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enapotamab vedotin1912424-97-5HuMax-AXL-ADCAntibody-Drug Conjugates (ADCs)EGFRTAM ReceptorAntibody-Drug ConjugatesEpidermal growth factor receptorErbB-1HER1Tyro3AxlMerInhibitorinhibitorinhibit

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