ent-17-Hydroxykauran-3-one (Synonyms: ent-Kaurane-3-oxo-17β-ol)

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ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana.

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ent-17-Hydroxykauran-3-one Chemical Structure

CAS No. : 960589-81-5

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Description

ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	> 5 μM Compound: 5	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method	[PMID: 34236840]
MDA-MB-231	IC₅₀	> 5 μM Compound: 5	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method	[PMID: 34236840]
MDA-MB-468	IC₅₀	> 5 μM Compound: 5	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 96 hrs by MTT method	[PMID: 34236840]

Molecular Weight

304.47

Formula

C₂₀H₃₂O₂

CAS No.

960589-81-5

SMILES

C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C(C)(C(CC2)=O)C)C[C@](CC3)([H])[C@H](C4)CO

Structure Classification

Initial Source

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Shi Q, et, al. Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana. Bioorg Med Chem Lett. 2017 Jan 15;27(2):266-270. [Content Brief]

ent-17-Hydroxykauran-3-one Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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