2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Entolimod

Entolimod (CBLB-502), a recombinant protein is a toll-like receptor 5 (TLR5) agonist. Entolimod induces a cascade of TLR5-NF-κB signaling resulting in mobilization to the liver of various components of innate and adaptive immunity, followed by suppression of liver metastases and development of long-term antitumor immune memory.

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Entolimod Chemical Structure

Entolimod Chemical Structure

CAS No. : 951628-22-1

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Entolimod Related Antibodies

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Description

Entolimod (CBLB-502), a recombinant protein is a toll-like receptor 5 (TLR5) agonist. Entolimod induces a cascade of TLR5-NF-κB signaling resulting in mobilization to the liver of various components of innate and adaptive immunity, followed by suppression of liver metastases and development of long-term antitumor immune memory[1][2].

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[Entolimod]
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Purity & Documentation
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Entolimod Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Entolimod951628-22-1CBLB-502CBLB502CBLB 502Toll-like Receptor (TLR)TLR5-NF-κBTLR5 agonistimmunotherapeutic agenthepatic metastasisInhibitorinhibitorinhibit

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