Epi-cryptoacetalide 

Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with K_i values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities^[1].

Ki: 0.3 μM (ER-α) and 1.92 μM (EP2 subtype)^[1]

Epi-cryptoacetalide is one of the ingredients contained in Salvia miltiorrhiza which is known to have properties in removing blood stasis and relieving pain, activating blood to promote menstruation, relieving restlessness; irregular menstruation, amenorrhea, menalgia, mass in the abdomen, stabbing pain in the chest and abdomen, pyretic arthralgia, ulcers and sores, sleeplessness, swelling of the liver and spleen, angina pectoris^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

286.37

C₁₈H₂₂O₃

132152-57-9

O=C1O[C@@]2(OC[C@@H](C2)C)C3=CC=C(C(C)(CCC4)C)C4=C31

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Herbert Situmorang, et al. IN-SILICO dynamic analysis of Sulawesi propolis as anti-endometriosis drug: Interaction study with TNF alpha receptor, NF-kB, estrogen receptor, progesterone receptor and prostaglandin receptor. Ann Med Surg (Lond). 2021 Jun 17;67:102459.  [Content Brief]