1. Anti-infection
  2. Antibiotic Bacterial
  3. Eremomycin

Eremomycin  (Synonyms: MM 45289; A 82846A)

Cat. No.: HY-105282 Purity: 95.87%
COA Handling Instructions

Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL.

For research use only. We do not sell to patients.

Eremomycin Chemical Structure

Eremomycin Chemical Structure

CAS No. : 110865-90-2

Size Price Stock Quantity
1 mg USD 400 In-stock
5 mg USD 1200 In-stock
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Description

Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL[1].

Molecular Weight

1557.99

Formula

C73H89ClN10O26

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@](N)([C@H]([C@@H](O1)C)O)C[C@@H]1O[C@@H]([C@]2([H])NC([C@](C3=CC=C(O)C(C4=C(O)C=C(O)C=C4[C@H](NC2=O)C(O)=O)=C3)([H])NC([C@]5([H])NC([C@@H](NC([C@@H]([C@@H](C6=CC=C(O7)C(Cl)=C6)O)NC([C@H](NC)CC(C)C)=O)=O)CC(N)=O)=O)=O)=O)C8=CC=C(C=C8)OC9=CC5=CC7=C9O[C@H]%10[C@@H]([C@H]([C@@H]([C@H](O%10)CO)O)O)O[C@H]%11C[C@](N)([C@H]([C@@H](O%11)C)O)C

Structure Classification
Initial Source

Amycolatopsis orientalis

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (64.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6419 mL 3.2093 mL 6.4185 mL
5 mM 0.1284 mL 0.6419 mL 1.2837 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6419 mL 3.2093 mL 6.4185 mL 16.0463 mL
5 mM 0.1284 mL 0.6419 mL 1.2837 mL 3.2093 mL
10 mM 0.0642 mL 0.3209 mL 0.6419 mL 1.6046 mL
15 mM 0.0428 mL 0.2140 mL 0.4279 mL 1.0698 mL
20 mM 0.0321 mL 0.1605 mL 0.3209 mL 0.8023 mL
25 mM 0.0257 mL 0.1284 mL 0.2567 mL 0.6419 mL
30 mM 0.0214 mL 0.1070 mL 0.2140 mL 0.5349 mL
40 mM 0.0160 mL 0.0802 mL 0.1605 mL 0.4012 mL
50 mM 0.0128 mL 0.0642 mL 0.1284 mL 0.3209 mL
60 mM 0.0107 mL 0.0535 mL 0.1070 mL 0.2674 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Eremomycin
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