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  2. Peptide and Derivatives
  3. Inhibitors and Substrates
  4. Ion Channel Modulators
  5. Ergtoxin-1

Ergtoxin-1 is a potassium channel blocker. Ergtoxin-1 is isolated from the venom of the Mexican scorpion Centruroides noxius. Ergtoxin 1 can block ERG-K+ channels in nerve, heart and endocrine cells.

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Ergtoxin-1 Chemical Structure

Ergtoxin-1 Chemical Structure

CAS No. : 304436-85-9

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Description

Ergtoxin-1 is a potassium channel blocker. Ergtoxin-1 is isolated from the venom of the Mexican scorpion Centruroides noxius. Ergtoxin 1 can block ERG-K+ channels in nerve, heart and endocrine cells[1].

Molecular Weight

4730.29

Formula

C193H287N59O63S9

CAS No.
Sequence

Asp-Arg-Asp-Ser-Cys-Val-Asp-Lys-Ser-Arg-Cys-Ala-Lys-Tyr-Gly-Tyr-Tyr-Gln-Glu-Cys-Gln-Asp-Cys-Cys-Lys-Asn-Ala-Gly-His-Asn-Gly-Gly-Thr-Cys-Met-Phe-Phe-Lys-Cys-Lys-Cys-Ala (Disulfide bridge:Cys5-Cys23;Cys11-Cys34;Cys20-Cys39;Cys24-Cys41)

Sequence Shortening

DRDSCVDKSRCAKYGYYQECQDCCKNAGHNGGTCMFFKCKCA (Disulfide bridge:Cys5-Cys23;Cys11-Cys34;Cys20-Cys39;Cys24-Cys41)

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ergtoxin-1
Cat. No.:
HY-P5806
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