ESAT6 Epitope 

ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC₅₀=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity^[1].

2123.30

C₉₂H₁₃₉N₂₅O₃₁S

183273-40-7

Solid

White to off-white

Met-Thr-Glu-Gln-Gln-Trp-Asn-Phe-Ala-Gly-Ile-Glu-Ala-Ala-Ala-Ser-Ala-Ile-Gln-Gly

MTEQQWNFAGIEAAASAIQG

OC(CNC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](CO)NC([C@H](C)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Chesson, et al. "Nanoscale peptide self-assemblies boost BCG-primed cellular immunity against Mycobacterium tuberculosis." Scientific reports 8.1 (2018): 12519.  [Content Brief]