Estradiol 3-glucuronide 

Estradiol 3-glucuronide is an immunogen with antigenic properties. Estradiol 3-glucuronide induced antiserum in the rabbit possesses high afinity and specifcity to Estradiol 3-glucuronide. Estradiol 3-glucuronide is promising for research of radioimmunoassay^[1][2].

448.51

C₂₄H₃₂O₈

15270-30-1

Solid

White to off-white

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)C=C4CC3

Room temperature in continental US; may vary elsewhere.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Nambara T, et al. A direct radioimmunoassay of estradiol 3-glucuronide using specific antiserum. Chem Pharm Bull (Tokyo). 1983 Oct;31(10):3583-8.  [Content Brief]

  [2]. Gerk PM, et al. Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide. Drug Metab Dispos. 2004 Oct;32(10):1139-45.  [Content Brief]