2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Estrogen Receptor/ERR Endogenous Metabolite
  4. Estriol-d2

Estriol-d2 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

For research use only. We do not sell to patients.

Estriol-d<sub>2</sub> Chemical Structure

Estriol-d2 Chemical Structure

CAS No. : 53866-32-3

Size Price Stock Quantity
500 μg USD 140 In-stock
1 mg USD 230 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Estriol-d2:

Estriol-d2 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

Estriol-d2 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Estriol-d2 Related Antibodies
Molecular Weight

290.39

Formula

C18H22D2O3
CAS No.
Unlabeled CAS

50-27-1
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(C=C2C(CC[C@@]3([C@@]2(CC[C@]4([C@]3(C[C@H]([C@@H]4O)O)[H])C)[H])[H])=C1[2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (860.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4436 mL 17.2182 mL 34.4364 mL
5 mM 0.6887 mL 3.4436 mL 6.8873 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.47%

SDS (393 KB)

COA (250 KB) HNMR (416 KB) RP-HPLC (598 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4436 mL 17.2182 mL 34.4364 mL 86.0911 mL
5 mM 0.6887 mL 3.4436 mL 6.8873 mL 17.2182 mL
10 mM 0.3444 mL 1.7218 mL 3.4436 mL 8.6091 mL
15 mM 0.2296 mL 1.1479 mL 2.2958 mL 5.7394 mL
20 mM 0.1722 mL 0.8609 mL 1.7218 mL 4.3046 mL
25 mM 0.1377 mL 0.6887 mL 1.3775 mL 3.4436 mL
30 mM 0.1148 mL 0.5739 mL 1.1479 mL 2.8697 mL
40 mM 0.0861 mL 0.4305 mL 0.8609 mL 2.1523 mL
50 mM 0.0689 mL 0.3444 mL 0.6887 mL 1.7218 mL
60 mM 0.0574 mL 0.2870 mL 0.5739 mL 1.4349 mL
80 mM 0.0430 mL 0.2152 mL 0.4305 mL 1.0761 mL
100 mM 0.0344 mL 0.1722 mL 0.3444 mL 0.8609 mL
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Estriol-d2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estriol-d253866-32-3Estrogen Receptor/ERREndogenous MetaboliteInhibitorinhibitorinhibit

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