Estrone acetate  (Synonyms: Hogival; Oestrone-3-acetate; Puboestrene)

Estrone acetate is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density). Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models^[1].

312.40

C₂₀H₂₄O₃

901-93-9

C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OC(C)=O)=C4)[C@@]3([H])CC1)C2=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. McComb DJ, et al. Enhanced responsiveness of lactotrophs in ectopic pituitaries to bromocryptine and estrone acetate. Acta Anat (Basel). 1981;110(2):113-20.  [Content Brief]