1. PI3K/Akt/mTOR Cell Cycle/DNA Damage Autophagy Apoptosis Immunology/Inflammation Anti-infection
  2. mTOR FKBP Autophagy Apoptosis Bacterial
  3. Everolimus (Standard)

Everolimus (Standard)  (Synonyms: RAD001 (Standard); SDZ-RAD (Standard))

Cat. No.: HY-10218R Purity: ≥98%
Handling Instructions

Everolimus (Standard) is the analytical standard of Everolimus. This product is intended for research and analytical applications. Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities.

For research use only. We do not sell to patients.

Everolimus (Standard) Chemical Structure

Everolimus (Standard) Chemical Structure

CAS No. : 159351-69-6

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Description
Molecular Weight

958.22

Formula

C53H83NO14

CAS No.
SMILES

O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](OCCO)CC4)OC)C)=O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Everolimus (Standard)
Cat. No.:
HY-10218R
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