Evogliptin hydrochloride (Synonyms: DA-1229 hydrochloride)

Cat. No.: HY-117985A: FAQs
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Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation.

For research use only. We do not sell to patients.

Evogliptin hydrochloride Chemical Structure

CAS No. : 1246960-27-9

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Other Forms of Evogliptin hydrochloride:

Evogliptin Get quote
Evogliptin tartrate Get quote

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Description	Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation^[1].
Molecular Weight	437.88
Formula	C₁₉H₂₇ClF₃N₃O₃
CAS No.	1246960-27-9
SMILES	O=C1NCCN([C@@H]1COC(C)(C)C)C(C[C@@H](CC2=CC(F)=C(C=C2F)F)N)=O.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Kim M K, et al. Prevention and treatment effect of evogliptin on hepatic steatosis in high-fat-fed animal models[J]. Archives of pharmacal research, 2017, 40(2): 268-281. [Content Brief]

Evogliptin hydrochloride Related Classifications

Metabolic Disease Endocrinology

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Evogliptin1246960-27-9DA-1229DA1229DA 1229Dipeptidyl PeptidaseDPPInhibitorinsulin resistancefall blood sugarDPP-4glp-1inhibitorinhibit

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Evogliptin hydrochloride (Synonyms: DA-1229 hydrochloride)

Other Forms of Evogliptin hydrochloride:

Evogliptin hydrochloride Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

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Biological Activity

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References

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