2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Exserohilone

Exserohilone ((-)-Exserohilone) is a thiodiketopiperazine derivative that exhibits the inhibition of TNF-α-induced ROS generation and MMP-1 secretion. Exserohilone increases the procollagen type I α1 secretion in human dermal fibroblasts.

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Exserohilone Chemical Structure

Exserohilone Chemical Structure

CAS No. : 99572-22-2

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Exserohilone Related Antibodies

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Description

Exserohilone ((-)-Exserohilone) is a thiodiketopiperazine derivative that exhibits the inhibition of TNF-α-induced ROS generation and MMP-1 secretion. Exserohilone increases the procollagen type I α1 secretion in human dermal fibroblasts[1].

Molecular Weight

450.53

Formula

C20H22N2O6S2
CAS No.
SMILES

CS[C@@]12N(C([C@@]3(N([C@]4([H])[C@@](C(C=C[C@H]4O)=O)([H])C3)C2=O)SC)=O)[C@]5([H])[C@@](C(C=C[C@H]5O)=O)([H])C1
Structure Classification
Initial Source

Exserohilum holmii
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Exserohilone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exserohilone99572-22-2(-)-ExserohiloneReactive Oxygen Speciesthiodiketopiperazine derivativeTNF-αMMP-1anti-skin aging effectsInhibitorinhibitorinhibit

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