Ezetimibe hydroxy glucuronide (Synonyms: SCH 488128; Ezetimibe hydroxy β-D-Glucuronide)

Cat. No.: HY-135245: FAQs
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Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376).

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Ezetimibe hydroxy glucuronide Chemical Structure

CAS No. : 536709-33-8

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Other Forms of Ezetimibe hydroxy glucuronide:

Ezetimibe Hydroxy-d4 β-D-Glucuronide Get quote

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Description	Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376)^[1].
Molecular Weight	585.55
Formula	C₃₀H₂₉F₂NO₉
CAS No.	536709-33-8
SMILES	O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1O[C@H](C2=CC=C(F)C=C2)CC[C@@H]3[C@@H](C4=CC=C(O)C=C4)N(C5=CC=C(F)C=C5)C3=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Anima Ghosal, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. [Content Brief] [2]. Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. [Content Brief]

Ezetimibe hydroxy glucuronide Related Classifications

Cardiovascular Disease

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	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ezetimibe hydroxy glucuronide536709-33-8SCH 488128 Ezetimibe hydroxy β-D-GlucuronideSCH488128SCH-488128Drug MetaboliteInhibitorinhibitorinhibit

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Ezetimibe hydroxy glucuronide (Synonyms: SCH 488128; Ezetimibe hydroxy β-D-Glucuronide)

Other Forms of Ezetimibe hydroxy glucuronide:

Ezetimibe hydroxy glucuronide Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review