2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. FAK-IN-6

FAK-IN-6 is a potent FAK inhibitor with an IC50 value of 1.415 nM. FAK-IN-6 has anti-proliferative activity against certain cancer cell lines. FAK-IN-6 can be used for researching pancreatic cancer.

For research use only. We do not sell to patients.

FAK-IN-6 Chemical Structure

FAK-IN-6 Chemical Structure

CAS No. : 3033299-38-3

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FAK-IN-6 Related Antibodies

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Description

FAK-IN-6 is a potent FAK inhibitor with an IC50 value of 1.415 nM. FAK-IN-6 has anti-proliferative activity against certain cancer cell lines. FAK-IN-6 can be used for researching pancreatic cancer[1].

IC50 & Target

IC50: 1.415 nM (FAK)[1]
In Vitro

FAK-IN-6 (compound 9h) (0-10 μM; 72 h) has anti-proliferative activity against pancreatic cancer cells, lung cancer cells and lymphoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FAK-IN-6 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: AsPC-1, PaCa-2, H1975, KM3/BTZ, Raji and L-02[1]
Concentration: 0-10 μM
Incubation Time: 72 h
Result: Exhibited anti-proliferative activity against AsPC-1, PaCa-2, H1975, KM3/BTZ, Raji and L-02 with IC50s of 0.9886 ± 0.0086 μM, 5.274 ± 0.9312 μM, 2.918 ± 0.0821 μM, 2.315 ± 0.2969 μM, 1.320 ± 0.2973 μM and 1.220 ± 0.2683 μM.
Molecular Weight

596.04

Formula

C25H31ClN5O6PS
CAS No.
SMILES

O=C(NC1=CC=C(NC2=NC=C(Cl)C(NC3=CC=CC=C3S(=O)(C(C)C)=O)=N2)C=C1)CP(OCC)(OCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FAK-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAK-IN-63033299-38-3FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseAnticancerpancreatic cancerlung cancerlymphomaInhibitorinhibitorinhibit

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