1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  2. EGFR
  3. Falnidamol (Standard)

Falnidamol (Standard)  (Synonyms: BIBX 1382 (Standard))

Cat. No.: HY-10322R Purity: ≥98%
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Falnidamol (Standard) is the analytical standard of Falnidamol. This product is intended for research and analytical applications. Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50>10 μM). Falnidamol is a pyrimido-pyrimidine compound and has anti-cancer activity[1][2].

For research use only. We do not sell to patients.

Falnidamol (Standard) Chemical Structure

Falnidamol (Standard) Chemical Structure

CAS No. : 196612-93-8

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Description
Molecular Weight

387.84

Formula

C18H19ClFN7

CAS No.
SMILES

ClC1=CC(NC2=NC=NC3=CN=C(NC(CC4)CCN4C)N=C23)=CC=C1F

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Falnidamol (Standard)
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HY-10322R
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