2. Cytoskeleton Cell Cycle/DNA Damage Neuronal Signaling Membrane Transporter/Ion Channel Autophagy Stem Cell/Wnt TGF-beta/Smad Epigenetics Anti-infection
  3. ROCK Calcium Channel Autophagy PKA PKC HIV
  4. Fasudil Hydrochloride (Standard)

Fasudil Hydrochloride (Standard) 

Cat. No.: HY-10341R Purity: ≥98%
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Fasudil (Hydrochloride) (Standard) is the analytical standard of Fasudil (Hydrochloride). This product is intended for research and analytical applications. Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator.

For research use only. We do not sell to patients.

Fasudil Hydrochloride (Standard) Chemical Structure

Fasudil Hydrochloride (Standard) Chemical Structure

CAS No. : 105628-07-7

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Description

Fasudil (Hydrochloride) (Standard) is the analytical standard of Fasudil (Hydrochloride). This product is intended for research and analytical applications. Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator.

Molecular Weight

327.83

Formula

C14H18ClN3O2S
CAS No.
SMILES

O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Fasudil Hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fasudil Hydrochloride (Standard)105628-07-7ROCKCalcium ChannelAutophagyPKAPKCHIVRho-associated protein kinaseRho-associated kinaseRho-kinaseROKCa2+ channelsCa channelsProtein kinase AProtein kinase CHuman immunodeficiency virusorally activeprotein kinasescollagena-SMATIMP-1ERK1/2JNKp38rat HSCshuman HSCTWNT-4 cellsCa2+ channel antagonistvasodilatorlysophoaphatidic acidLPAInhibitorinhibitorinhibit

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