2. Cell Cycle/DNA Damage Anti-infection
  3. DNA/RNA Synthesis Influenza Virus SARS-CoV Bacterial
  4. Favipiravir sodium

Favipiravir sodium  (Synonyms: T-705 sodium)

Cat. No.: HY-14768A
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Favipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM.

For research use only. We do not sell to patients.

Favipiravir sodium Chemical Structure

Favipiravir sodium Chemical Structure

CAS No. : 1366418-99-6

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Favipiravir sodium Related Antibodies

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40 Publications Citing Use of MCE Favipiravir sodium

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    Favipiravir sodium purchased from MedChemExpress. Usage Cited in: BMC Vet Res. 2019 Sep 2;15(1):316.  [Abstract]

    Comparisons of antiviral effects of T-705 and anti-CDV polyclonal serum. The Vero and DH82 cells were treated with T-705 (156.25 μg/ml), anti-CDV polyclonal serum (1:128) and a combination of T-705 (156.25 μg/ml) and anti-CDV polyclonal serum (1:128) at 0, 12, 24, 36 and 48 h p.i. with CDV-3 and CDV-11 at a MOI of 0.1. The mock groups were treated with DMEM p.i. at the same times. Viral replications in cells were detected by IFA and the mean fluorescence percentages (a, c, e, g) were calculated

    Favipiravir sodium purchased from MedChemExpress. Usage Cited in: BMC Vet Res. 2019 Sep 2;15(1):316.  [Abstract]

    Comparisons of antiviral effects of T-705 and anti-CDV polyclonal serum. The Vero and DH82 cells were treated with T-705 (156.25 μg/ml), anti-CDV polyclonal serum (1:128) and a combination of T-705 (156.25 μg/ml) and anti-CDV polyclonal serum (1:128) at 0, 12, 24, 36 and 48 h p.i. with CDV-3 and CDV-11 at a MOI of 0.1. The mock groups were treated with DMEM p.i. at the same times. The virus titers in supernatant (b, d, f, h) were determined and compared with the viral titers in mock group. All e

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    Description

    Favipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM[1][2].

    Molecular Weight

    179.08

    Formula

    C5H3FN3NaO2
    CAS No.
    SMILES

    O=C(C1=NC(F)=CN=C1O[Na])N
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
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    Favipiravir sodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Favipiravir1366418-99-6T-705T705T 705DNA/RNA SynthesisInfluenza VirusSARS-CoVBacterialSARS coronavirusInhibitorinhibitorinhibit

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