1. Apoptosis Autophagy
  2. Ferroptosis Apoptosis Autophagy
  3. Ferroptocide

Ferroptocide is a cell death inducer that triggers ferroptosis and has anti-tumor activity. Ferroptocide can induce oxidative stress, leading to G2/M cell cycle arrest and apoptosis activation in LNCaP cells, while also effectively inhibiting the cell viability of both LNCaP and TRAMP-C1 cells. Ferroptocide can be used to study its capability to induce mitochondrial autophagy and to trigger immunogenic cell death (ICD) in prostate cancer cells.

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Ferroptocide Chemical Structure

Ferroptocide Chemical Structure

CAS No. : 2505218-38-0

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Description

Ferroptocide is a cell death inducer that triggers ferroptosis and has anti-tumor activity. Ferroptocide can induce oxidative stress, leading to G2/M cell cycle arrest and apoptosis activation in LNCaP cells, while also effectively inhibiting the cell viability of both LNCaP and TRAMP-C1 cells. Ferroptocide can be used to study its capability to induce mitochondrial autophagy and to trigger immunogenic cell death (ICD) in prostate cancer cells[1].

Molecular Weight

586.08

Formula

C30H36ClN3O7

CAS No.
SMILES

O[C@@]12[C@@]3(C[C@@H](C2=O)O)[C@H]([C@H](C4=CCN(C(N(C5=CC=CC=C5)C6=O)=O)N6C4)C[C@H]([C@@]1([C@@H](CC3)C)C)OC(CCl)=O)C

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ferroptocide
Cat. No.:
HY-158775
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