1. Oligonucleotides
  2. Antisense Oligonucleotides
  3. Fesomersen sodium

Fesomersen sodium  (Synonyms: ION-957943; BAY-2976217; IONIS-FXI-LRx sodium)

Cat. No.: HY-139788A
COA Handling Instructions

Fesomersen (sodium) is an antisense oligonucleotide designed to inhibit the production of Factor XI.

For research use only. We do not sell to patients.

DNA, d([2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC-A-sp-T-sp-T-sp-G-sp-G-sp-T-sp-G-sp-m5C-sp-A-sp-m5C-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate], sodium salt (1:20)

Fesomersen sodium Chemical Structure

CAS No. : 2380288-85-5

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Description

Fesomersen (sodium) is an antisense oligonucleotide designed to inhibit the production of Factor XI.

Clinical Trial
Molecular Weight

9113.01

Formula

C296H434N82O156P20S13Na20

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

[Fesomersen (sodium)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Fesomersen sodium Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Fesomersen sodium
Cat. No.:
HY-139788A
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