2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR-IN-2

FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research.

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FGFR-IN-2 Chemical Structure

FGFR-IN-2 Chemical Structure

CAS No. : 2665665-09-6

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FGFR-IN-2 Related Antibodies

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Description

FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].

IC50 & Target[1]

FGFR1

7.3 nM (IC50)

FGFR2

4.3 nM (IC50)

FGFR3

7.6 nM (IC50)

FGFR4

11 nM (IC50)

Molecular Weight

446.54

Formula

C25H30N6O2
CAS No.
SMILES

CN1N=CC(C2=NN=C3C=CC(N(C4=CC(OC)=CC(OC)=C4)CCNC(C)C)=CC3=C2)=C1
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Purity & Documentation
References
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FGFR-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR-IN-22665665-09-6FGFRFibroblast growth factor receptorInhibitorinhibitorinhibit

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