1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR3-IN-4

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1.

For research use only. We do not sell to patients.

FGFR3-IN-4 Chemical Structure

FGFR3-IN-4 Chemical Structure

CAS No. : 2833706-13-9

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Description

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

IC50 & Target[1]

FGFR3

< 50 nM (IC50)

In Vitro

FGFR3 (example 297) inhibits FGFR3 with an IC50 value of less than 50 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

485.97

Formula

C26H24ClN7O

CAS No.
SMILES

C[C@H](C1=C(C=CC=C1)C#N)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(Cl)C=N5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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FGFR3-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FGFR3-IN-4
Cat. No.:
HY-148778
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