2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR4-IN-9

FGFR4-IN-9 (Compound 6O) is a selective FGFR4 inhibitor with an IC50 of 75.3 nM. FGFR4-IN-9 effectively inhibits both the growth and angiogenesis of HCC.

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FGFR4-IN-9 Chemical Structure

FGFR4-IN-9 Chemical Structure

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FGFR4-IN-9 Related Antibodies

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Description

FGFR4-IN-9 (Compound 6O) is a selective FGFR4 inhibitor with an IC50 of 75.3 nM. FGFR4-IN-9 effectively inhibits both the growth and angiogenesis of HCC[1].

IC50 & Target

FGFR4

75.3 nM (IC50)

Molecular Weight

522.90

Formula

C24H22ClF3N4O4
SMILES

C=CC(NC1=CC(F)=CC(Cl)=C1NC2=NC(C)=C(C(C)=N2)OCC3=C(C(OC)=CC(OC)=C3F)F)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FGFR4-IN-9 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR4-IN-9FGFRFibroblast growth factor receptorHep3BHCCHuh7H6c7hepatocellular carcinomaantitumor effectInhibitorinhibitorinhibit

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