Flavin adenine dinucleotide-¹³C₅ ammonium  (Synonyms: FAD-¹³C₅ ammonium)

Flavin adenine dinucleotide-¹³C5 (FAD-¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

C₂₂¹³C₅H₃₃N₉O₁₅P₂.xNH₃

146-14-5

CC1=CC(N=C2C(N3)=O)=C(C=C1C)N(C[C@@H]([C@@H]([C@@H](COP(O)(OP(O)(O[13CH2][13C@H]4O[13C@@H](N5C=NC6=C(N=CN=C56)N)[13C@@H]([13C@@H]4O)O)=O)=O)O)O)O)C2=NC3=O.[x].N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Sugiyama S, et al. Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. Jpn Heart J. 1979 Sep;20(5):657-65.  [Content Brief]

  [3]. Karyakin AA, et al. Electropolymerized flavin adenine dinucleotide as an advanced NADH transducer. Anal Chem. 2004 Apr 1;76(7):2004-9.  [Content Brief]